Serenus.AI

AI-powered prior authorization and clinical decision support for health insurance payers and providers

Underwriting & Risk Startup Seed

Overview

Serenus.AI is an underwriting and risk management platform for health insurance payers and healthcare providers, focused on medical prior authorization and utilization review. The company develops generative AI systems that automate and support clinical decision-making for elective procedures, reducing administrative burden and unnecessary care costs for health plans, carriers, and medical administrators operating in Israel, the United Kingdom, and the United States.

The platform combines machine learning with clinical knowledge to replicate the decision-making logic of specialist physicians on a case-by-case basis. Its flagship product, AI Prior-Auth Connect, integrates with payer and provider workflow systems to evaluate authorization requests for common elective procedures such as knee replacements. The system holds a US patent for its automated screening and prevention methodology and supports 30+ clinical modules across procedure types.

Founded in 2017 by a team combining technology and clinical expertise, Serenus.AI has raised USD 2.5M in seed funding from Israeli venture capital firms and received grants from four Israeli government bodies including the Ministry of Health and the BIRD Foundation. The company has won recognition at the MTL Tech Awards 2020 and is listed in The Digital Insurer InsurTech Directory under Underwriting & Risk Management.

Products & Services

AI Prior-Auth Connect

Co-developed with HealthTrio, AI Prior-Auth Connect automates the medical prior authorization process for health plans and payers. The product integrates Serenus.AI's generative AI with HealthTrio's provider-payer platform, which serves 2 million+ provider users and 10 million+ healthcare patients across top-rated US health plans.

Key Features

Autonomous, clinically objective case-by-case authorization review using patented generative AI
30+ clinical modules covering common elective procedures including knee replacement
Designed to improve care quality while reducing medical and administrative costs
Compatible with existing health plan and provider workflows

Target Users: Health plans, payers, and healthcare administrators in the US, UK, and Israel

Clinical Decision Support

A core AI system that replicates expert physician decision-making by synthesizing updated clinical research, professional knowledge, and machine learning outputs. Designed to help medical professionals make evidence-based, personalized patient decisions.

Key Features

Integrates current medical research and practice guidelines
Applies machine learning to clinical knowledge for each patient case
Delivers objective, consistent recommendations at the point of care

Target Users: Physicians, medical professionals, health system administrators

At a Glance

Founded: 2017
Headquarters: Tel Aviv, Israel
Employees: 11-50
Funding: Seed

Category & Focus

Category: Underwriting & Risk
Subcategories: Medical Prior Authorization Utilization Review Clinical Decision Support
Insurance Verticals: Health
Target Customers: Carriers, TPAs